Neural tube defects [NTDs] are the disorders caused due to non closure of neural tube during 3^rd to 4^th week of embryonic period. NTDs have an incidence of 1–2 per 1000 births. Major types of NTDs include anencephaly, spinabifida, craniorachischisis, encephalocele, inencephaly. Present study was carried out to study craniorachischisis and associated malformations. Method: study was carried out on 24 weeks aborted female fetus showing gross neural tube defect, in department of anatomy. Result: fetus was having craniorachischisis i.e. complete failure of neurulation along with facial dismorphism and other malformations.