IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-8-16263 Original Research Paper EPIDEMIOLOGICAL EVALUATION OF PARATHYROID HORMONE IN UROLITHIASIS Agarwal Dr. Vinay Tomar Dr. Shivam Priyadarshi Dr. August 2018 7 8 01 02 ABSTRACT

Background: Hyperparathyroidism has been reported to account for as many as 5–8% of all calcium stone formers. Around 15–21 % patients will have renal calculi as their presenting complaints.Aim of this study is to identify the metabolic derangement in association with PTH hormone in patients of urolithiasis.

 

 

Methods: All patients with urolithiasis(renal and/or ureteric) were evaluated for parathyroid hormone. Patients were divided in two groups – group A (with normal PTH level = 4.7–114 pg/ml) and group B (with raised PTH = >114pg/ml). Patients with raised creatinine(>1.6), known case of hyperparathyroidism and those who refused for PTH evaluation were excluded from study.

Results: Total of 230 patients were available for analysis out of which 22 patients had raised PTH.PTH was significantly raised in recurrent (p=.02), staghorn calculi (p=.01) and with stone burden >2.5cm.

 

Conclusions: Ours is probably the 1st study to evaluate ureteric calculi and stone burden in association to raised PTH. Young age, Bilateral, recurrent and larger stones are more prone to have raised PTH.