BACKGROUND :. Chronic Kidney Disease ( CKD ) is one of the most common causes of morbidity and mortality due to renal causes. CKD is classified as per the glomerular filtration rate ( GFR). The fifth stage of the CKD when the GFR is less than 15 ml/min/ 1.73 m² is called the End Stage Renal Disease ( ESRD ).

AIMS AND OBJECTIVES : To study the  clinical and epidemiological  profile of End Stage Renal Disease  ( ESRD)   patients undergoing renal  transplantation  in a tertiary care center .

METHODS : Atotal of 120 patients of End Stage Renal Disease ( ESRD ) admitted for renal transplantation were enrolled  in our study. Clinical  and epidemiological profile of  these patients was observed in our study.

RESULTS :  Majority of the patients in our study were males ( 86 patients , 72 % ) with a male : female ratio of 2.5 : 1. Diabetic Nephropathy was the most common aetiology of End Stage Renal Disease ( ESRD ) in our study.

CONCLUSION :  End Stage Renal Disease ( ESRD ) is the final stage of Chronic Kidney Disease ( CKD ). Identifying the patients in the early stages of CKD and treating the risk factors associated with it , constitutes the most important step in preventing the progressive renal damage. ESRD , once sets in requires some form of  renal replacement therapy : Haemodialysis or Renal Transplantation