Introduction: A study was designed to assess the benefits of low molecular weight dextran and its related complications in microsurgical reconstructions.

Materials &Methods: 20 consecutive patients undergoing microvascular reconstruction during a 1 year period were randomized into two groups. In the First group dextran–40 was administered in the postoperative period according to a standard protocol while the second group was not administered dextran.Flap outcome (survival of the flap) and the incidence of local and systemic complications were evaluated as the other outcome variables in the treatment groups.

Results and Discussion : Both the groups consisted of similar patient profile and type of flaps. The occurrences of local and systemic complications were similar in the both groups and no additional benefit or complications.The present study prospectively demonstrates no significance in addition of low molecular weight dextran in the intraoperative or postoperative scenario of microvascular reconstructions.