Aim:

          To evaluate the effects of low level laser therapy (LLLT) biostimulation following open flap debridement (OFD) and correlate with GCF levels of sclerostin in intrabony defect management.

Materials and methods:

          30 patients with 2 and 3 wall intrabony defects were treated using LLLT biostimulation along with OFD (n=15) and OFD alone (n=15). Patients were recalled at 3 and 6 months to assess the changes in sclerostin levels, Plaque index, Gingival index, Probing pocket depth, Clinical attachment level, Defect depth and gain in defect height.

Results:

          Both test and control groups showed a statistically significant improvement in all clinical parameters, sclerostin biomarker levels and defect depth from baseline to 3 and 6 months. However, the test group had a statistically significant reduction in defect depth at 3 to 6 months and the sclerostin biomarker levels also showed a statistically significant correlation to defect depth at all–time intervals.

Conclusion:

          Within limitations of the present study it can be concluded that LLLT has a greater benefit over OFD alone in intra bony defect regeneration as observed by progressive bone fill from 3 to 6 months.