Headache is a public health problem. This study is to evaluate refractive errors among subjects with migraine headache and to compare it with healthy subjects.This is a prospective cross–sectional study of 188 subjects with migraine headache, aged between 20 and 40 years and 180 subjects without headache of same age group as control group. Retinoscopy and subjective refraction was done to find out anisometropia and type of refractive errors; myopia, hypermetropia and astigmatism. Forty–nine (26.06%) subjects with migraine headache had refractive errors, out of which 29(59.18%) had astigmatism, 15(30.62%) had hypermetropia and 05(10.20%) had myopia. Out of 26(14.44%) cases in control group with refractive errors, 16(61.54%) had myopia, 07(26.92%) had astigmatism and 03(11.54%) had hypermetropia. Anisometropia was found in 14(7.45%) patients with migraine headache and in 07(3.89%) healthy subjects.  In this study, we observed that refractive error is a risk factor for migraine headache  in comparison to control group.