INTRODUCTION:W.H.O lists hemorrhage as the most common cause of maternal death .Thrombocytopenia though occurring in miniscule of the pregnant women, gives rise to serious maternal and neonatal complications if not detected or attended to.

OBJECTIVE: A comparative observational study to evaluate maternal morbidity in pregnant females with thrombocytopenia  during delivery in comparison with pregnant females without thrombocytopenia over a period of one year  in a Tertiary care hospital.

METHODS: Pregnant women with thrombocytopenia in labor were compared with the pregnant females without thrombocytopenia delivering consecutively, and evaluated for Mode of delivery, PPH, any need for blood and blood products, APH, DIC, MICU admission, maternal mortality, APGAR score, birth weight, meconium stained amniotic fluid, still birth, IUGR,NICU admission and neonatal mortality.

RESULTS: Association between qualitative variables was assessed by Chi–Square test, with   Continuity Correction for all 2 X 2 tables and by Fisher‘s Exact test for all 2 X 2 tables where Chi–Square test was not valid due to small counts. Gestational thrombocytopenia was the most common cause of thrombocytopenia (48%). PPH was significantly higher in patients of thrombocytopenia when compared to patients of non– thrombocytopenia. (p–value0.017 ). The rate of blood and blood products given to the pregnant patients with thrombocytopenia was high in the study as compared to the control group, and this was statistically significant.

CONCLUSIONS: Careful surveillance is required for pregnancies with thrombocytopenia for  early detection and treatment of possible complications with multidisciplinary approach, in order to try to reduce maternal and neonatal morbidities.