Background Neonatal sepsis is aleading cause of neonatal morbidity and mortality in India.The aim of this study was to identify predisposing factors for neonatal sepsis so as steps can be taken to minimize the same.

Material and Methods This was an observational cross sectionalprospective study conducted on 250 neonates brought to the out born nursery of Dr. Baba Saheb Ambedkar Hospital, with clinical features of sepsis. A detailed history including chief complaints, risk factors, past and family history, obstetric history and treatment details were recorded. Data was analysed using SPSS Statistical Software Version 15.0.

ResultIn the present study on outborn neonates admitted with sepsis 74.2% had late onset sepsis.49.6% of cases of neonatal sepsis had low birth weight and 36.8% were premature. Dai handling before delivery was present in 47.2% of the mothers of neonates in our study group. PROM was present in only 6.5% of cases and maternal fever and meconium stained liquor in 12.8% and 17.6% respectively.

ConclusionThere was a 1.55 times higher incidence of sepsis in males as compared to females. Neonatal sepsis was strongly associated with low birth weight  and prematurity. Dai handling before delivery was the single most important factor responsible for sepsis in outborn new borns. Pregnant women should be encouraged for regular antenatal check ups and institutional deliveries.