Introduction:Tonsillitis is one of the common diseases encountered regularly with different infectious causes.

Aims and Objectives:To enhance our understanding ofclinical and microbiological profile of tonsillitis.

Material and Methods: Observational, prospective study done on 100 patients over 1 year

Results and Observations:Clinical profile showed that 42 (42%) had acute parenchymatous tonsillitis, 28 (28%) had acute follicular tonsillitis, 30 (30%) had chronic tonsillitis. Microbiological profile showed that 70 (70%) were infected with group A beta haemolytic Streptococci, 8 (8%) with coagulase positive Staphylococci, 8 (8%) with coagulase positive Staphylococcus and Pneumococci, 6 (6%) with Klebsiella and Streptococci, 4 (4%) with pseudomonas and Klebsiella and 4 (4%) with Pneumococcus.

Conclusion: The study has highlighted the clinical profile and microbiological profile of tonsillitis in a tertiary care teaching hospital. Group A beta–haemolytic Streptococcus (GABHS) has emerged in more than two–thirds of patients and significant proportion of subjects had mixed infection.