IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-9-16604 Original Research Paper Quantitative Analysis of Saliva in Oral Submucous Fibrosis Patients – A Comparative Study Bharat Sumbh Dr. September 2018 7 9 01 02 ABSTRACT

Aim :To determine the salivary pH and salivary flow rate in patients with various stages of Oral submucous fibrosis (OSMF).

Materials and method: 100 patients were include in the study, and divided into five groups of 20 each, which are as follows :Control group (CB),Group A : stage I OSMF,Group B : stage II OSMF,Group C: stage III OSMF,Group D: stage IV A OSMF.

The patients were classified into OSMF stages according to Khanna & Andrade’s (9) classification based on mouth opening measurement. The Digital VernierCalliper was used for staging of OSMF patients by recording interincisal distance (mouth opening) in mm.Thespitting method of unstimulated saliva collection was carried out in a glass beaker calibrated in ml.

Results: The results obtained showed that as the stage of OSMF goes on increasing the salivary flow rate goes on decreasing. The difference between salivary flow rate of group B i.e. stage II & C i.e. stage III showed no significant difference. The pH was found to be 7 in control group and 6 in the OSMF groups which shows that in patients suffering from OSMF the saliva tend to be slightly acidic.

Conclusion:In this study we conclude that as the severity of OSMF increases the SFR goes on decreasing with the lowest in stage IV (i.e. group D) along with shift of the salivary pH in the acidic direction.