IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-9-16605 Original Research Paper The Effect of Medicaments used in Endodontic Regeneration on Root Dentin Fracture Strength – An in Vitro Study SNEHA SHREENIVAS VANAKI Dr. DR. SANDHYA KHASNIS Dr. September 2018 7 9 01 02 ABSTRACT

   The aim of thisin vitro study was to evaluate the effect of intracanal medicaments on root dentin fracture strength at different time intervals.

   Sixty single rooted extracted human permanent mandibular premolar teeth were used. Access opening,working length determination, biomechanical preparation weredone. The teeth were then randomly assigned as Group I – Triple antibiotic paste, Group II – Double antibiotic paste, Group III – Ca(OH)2 paste and Group IV – Control.Teeth were kept in normal saline solution, changed every weekand fracture strength was tested.

   There was percentage reduction in fracture strength with all the three medicamentsGroup I, II and IIIwhich was 30%, 27% and 27% respectively.

    GroupI showed maximum reduction in root dentin fracture strength.