IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-9-16608 Original Research Paper Neuroendocrine carcinoma of Esophagus–Presentation and Management: Case series Dr. Dr.Anupam Sharma Dr. Dr.Jitin Yadav Dr. Dr.Dwipen Kalita Dr. September 2018 7 9 01 02 ABSTRACT

Background:Neuroendocrine tumours of esophagus are a relatively rare disease with aggressive biology of tumour. We here present clinicopathological features and management of three cases.

Introduction:Neuroendocrine tumours of esophagus are rare tumours with incidence of 0.04–1.4 % of gastro intestinal neuroendocrine tumours(NETs) (1,2).The WHO classification system divides neuroendocrine neoplasms  (NENs) into low to intermediate grade(grade1–2 ) NETs and high grade (grade 3) neuroendocrine carcinomas( NECs ,large or small cell type) (3,4).Classified into two categories based on clinical symptoms and levels of hormone secretion into functional and nonfunctional (5).NETs of esophagus are found more commonly in men in the sixth decade of life (6).