Pediatric asthma is one of the most common chronic illnesses in childhood and affects the quality of life in children. Anti asthmatic drugs used in children may result in a variety of adverse drug reactions (ADR) and could contribute significantly to morbidity and mortality. Several studies report about the safety of asthma medications in adults but information in children is limited. Hence, we aimed to review literature to determine all the ADRs in pediatric patients of bronchial asthma.Pubmed database from Jan 2008 to Dec 2017 was searched for Randomised controlled clinical trials in children from 1–17 years of age that reported ADRs to asthma medications.Around 94 relevant articles were extracted, however, only those that could provide relevant information about ADRs in pediatric asthma were included. Most of the reported ADRs in reviewed studies are non–serious.Serious ADRs are relatively uncommon. However, the data available is very limited and extensive studies are necessary to further investigate long–term effects.