Background:COPD patients have high prevalence of elevated absolute eosinophil count.Significant number of COPD patients may also have bronchodilator reversibility.  This study assessed the predictive value of absolute eosinophil count for bronchodilator reversibility in COPD.

Objective:To find out the predictive value of absolute eosinophil count for bronchodilator reversibility in COPD

Materials and method:Cross sectional observational study in 120 patients with spirometry confirmed COPD after absolute eosinophil count estimation.  The predictive value of absolute eosinophil count for bronchodilator reversibility in COPD is assessed

Result: Positive and negative predictive value for peripheral blood eosinophilia in COPD for bronchodilator reversibility was found to be 60% (95% CI =40 – 77.14)and 36%(95% CI=25.3 – 48.29) respectively

Conclusion:Flow reversibility in COPD patients is associated with the degree of peripheral blood eosinophilia.