Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism which presents with hypokalemia and muscle weakness, more commonly seen in Asian men than women. The presence of elevated level of triiodothyronine (T₃) and thyroxine (T₄) and hypokalemia are the guiding signs towards the diagnosis. Prompt diagnosis and treatment are very important for preventing further damage. Treatment protocol includes correction of hypokalemia and achieving as well as maintaining the euthyroid state. We report the first such case from our hospital.