OBJECTIVE: The current study was undertaken to know the prevalence of ESBL producing Enterobacteriaceae at our tertiary health care centre in Jaipur,India.

MATERIALS AND METHODS: This study was carried out on 360 clinical isolates of E.coli, K. Pneumonia and Proteus species. The screening for ESBL production was done by the disc diffusion test  recommended by the Clinical and Laboratory Standards Institute (CLSI) and the screen positive isolates wereconfirmed by DDST,PDCT and E–strip test.

RESULTS: E.coli190(52.8%) was most common isolate. ESBL production was confirmed in 150 (41.7%) isolates. The isolates of E.coli 96(50.5%) were the most common ESBL producers.
CONCLUSION: There is a moderate prevalence of ESBL production in our hospital. Specific tests to detect ESBL production should be done routinely.