Background:

Lower levels of circulating cholesterol is risk factor for depressive disorder. A reduced serum cholesterol level may be accompanied by changes in viscosity and function of serotonin receptors and transporter.

Materials and Methods:

A total of 100 depressive patients and 100 healthy matched control subjects were recruited from mental hospital, Indore and lipid profile was measured.

Results:

Depression Patient group has shown significantly less triglyceride and significantly more HDL–c than control group.

Conclusion:

Lower levels of serum cholesterol are associated with depressive disorder.