Background:  Psoriasis is a skin disorder associated with  abnormal lipid prolife and decreased antioxidants.  Dyslipidemia  leads to  Cardiovascular diseases which increase mortality and morbidity in psoriasis patients .

Objectives:To estimate and compare lipid profile and Vitamin C levels in Psoriatic patients and healthy controls.

Materials and methods :A case control study was done on 80 individuals (40 Psoriatic patients as cases and 40  healthy controls ). Serum total cholesterol, triglycerides , high density lipoprotein and Vitamin C levels were estimated.

Results :The serum levels of total cholesterol,triglycerides, low density lipoprotein were significantly increased in cases whereas  high density lipoprotein and Vitamin C levels were decreased in cases as compared to controls.

Conclusion:Psoriasis is a high risk factor forCardiovascular diseases which can be prevented by early screening and treatment of hyperlipidemias .Vitamin C supplementation is recommended to prevent skin damage.