Head injury sustained due to road traffic accidents and other modes of traumatic brain injury have shown a progressive increase in emergency practice in general and neurosurgical care in particular. Adequate and clinical stratification of patients with regard to outcome and prognosis is of vital concern in reduction of mortality and morbidity in traumatic brain injury patients.The aim of the study is to study the significance of Glasgow Coma Scale and Madras Head Injury Prognostic Scale (MHIPS) as prognostic factors in traumatic brain injury. This analysis was done in a cohort of patients in the age group of 18 to 40 admitted with head injury during the two year period.   The main prognostic factors in traumatic main injury were analyzed. The study validates the importance of the basic clinical and radiological examination as quintessential prognostic markers in traumatic brain injury.