IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-10-16831 Original Research Paper Red blood cell distribution width: an emerging diagnostic marker for chronic periodontitis. Shivaraj B Warad Dr. Dr Karri Sri Laxmi Dr. Dr. Arati C Koregol Dr. Dr. Priya Sinha Dr. October 2018 7 10 01 02 ABSTRACT

Introduction:Periodontitis is an inflammatory disease of the supporting tissues of the teeth caused by specific microorganisms inducing a major vascular response which may impair erythropoiesis and degradation of erythrocytes.Red Blood Cell Distribution Width(RDW)is measurement of variation in size of the circulating erythrocytes(anisocytosis).

Aim:To evaluate RDW in chronic periodontitis(CP)and periodontally healthy subjects.

Materials and Methods:90 participants,45 CP and 45 healthy subjects were randomly selected from department of PMNM Dental College and Hospital. 4.5ml of blood was collected from all the subjects after obtaining informed consent and analysed for RDW.The obtained data werestatistically analysed.

Results:A statistically significant(p=0.006)and positive correlation was found between RDW of CP than the control group.

Conclusion:Increased RDW reflects chronic inflammation and increased oxidative stress,telltale signs of CP.RDW,a simple and inexpensive chair side diagnostic test can be used as reliable biomarker for early detection and therapeutic intervention in CP.