ABSTRACT

IJSR

International Journal of Scientific Research

2277 - 8179

Indian Society for Health and Advanced Research

ijsr-7-10-16846

Original Research Paper

GINGIVAL CREVICULAR FLUID PROCALCITONIN – A PIVOTAL MARKER IN TYPE II DIABETES WITH CHRONIC PERIODONTITIS

R.A

Jenifer Cynthia

Dr. Dr.J.Kavitha

Dr. Dr.

S.Lakshmisree

Dr.

October 2018

7 10 01 02 ABSTRACT

Aim: To determine the levels of procalcitonin in Gingival crevicular fluid ofType II diabetic patients with chronic periodontitis.

Materials and Method: Study included 24 males and grouped asGroup I (Healthy, n=8), Group II (Chronic periodontitis,n=8) andGroup III (Chronic periodontitis with type II DM, n=8). Plaque scores, bleeding scores, Probing depth, Clinical attachment loss,RBS and HbA1c were evaluated. GCF procalcitoninlevels wereanalyzed by ELISA.

Results:Significant increase inGCF procalcitonin levels in group III(CP+DM) at p<0.001.Periodontal destruction was more pronounced in group III(CP+DM) as assessed by periodontal clinical parameters (p<0.001)

Conclusion:

GCF procalcitonin reflects the periodontal disease activity in Type II Diabetics with chronic periodontitis and it can be used as a potential marker in these co–morbid conditions.