BACKGROUND: The primary goal of periodontal treatment is the maintenance of natural dentition in health and function. Present study was under taken to evaluate the efficacy of PLA–PGA copolymer(Fisiograft^®) gel in the treatment of infra–bony defects as compared with open flap debridement alone.

METHODOLOGY: Ten patients, aged 25–50 years with moderate to severe periodontitis. Two or more sites with ≥5 mm probing depth(PD), radiographic evidence of intra–osseous defects on opposite sides were selected. One defect was treated with Fisiograft^® gel(Test), other with open flap debridement alone(Control). At baseline, 3, 6, & 9 months clinical parameters and radiographs were evaluated and statistically analysed.

RESULTS: Study exhibited statistically no significant difference with both treatment modalities with all clinical parameters and radiographically with the defect fill.CONCLUSION: This study showed use of copolymer(Fisiograft^®) gel did not provide additional benefits over open flap debridement.