Aims:To identify the bacteriological and mycological aetiology of CSOM and to detect the antibiotic sensitivity pattern of the bacterial isolates.

Materials and Method: A total of 100 patients attending the Ear Nose &Throat (ENT) department, with complaints of ear discharge were included in the study. Two swabs were collected. First swab was used for gram staining and the second for culture and sensitivity.

Results: Culture reports showed 91% growth, of whichPseudomonas aeruginosa and Klebsiella sp were the mostpredominant species(35.23%). Fungal growth obtained hadCandida non–albicans as the predominant species followed by Aspergillus. Pseudomonas aeruginosa showed high sensitivity to Piperacillin–tazobactam (100%) and Tobramycin (100%) and was least sensitive to Ceftazidime(54%).

Conclusion:This study will help the clinicians in the ENT department to choose the appropriate treatment and formulate a protocol for empirical therapy.