Fungal infections are an important cause of morbidity and mortality in immune–compromised patients. Keeping in mind the above facts, the study was conducted to understand the prevalence of fungal meningitis in clinically suspected casesin Nair  Hospital, Mumbai,including 180 patients,who were clinically suspected for fungal meningitis.Collection and microbiological analysis of cerebrospinal fluid for identification of fungalisolates was carried out as per standard procedures. Total 35 fungal strains were isolated from total 180 cases and  Cryptococcusneoformansvarneoformansbeing the most prevalent strain followed by Candida species, causing fungal meningitis in HIV positive patients.There was significant association between fungal infections and HIV positivity.Amphotericin B was found to be the drug of choice for the fungal meningitis.