IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-11-17080 Original Research Paper CLINICOPATHOLOGICAL STUDY OF NON MELNOCYTIC EPIDERMAL AND APPENDEGEAL TUMOURS Srivastava Dr. November 2018 7 11 01 02 ABSTRACT

 

Background – Neoplasms of skin comprise a wide spectrum of benign and malignant tumours that

exhibit morphological differentiation towards one or more of structures found in normal skin. Benign tumours like seborrhoeic keratosis, skin tags barely attract the attention of the patient or the treating clinician and are  of cosmetic important  . In this study the histological features of selected but important benign and malignant non melanocytic skin tumours of keratinocytic and appendegeal origin were studied  with emphasis on histodiagnostic approach .

Material and method: A total of 102 histologically diagnosed skin tumours were included   in this study conducted over period of 24 months.

Result: Out of 102 cases studied there were  57 (55.88%) keratinocytic and  45 (44.11%) appendegeal tumours. 42.2% of patients were in the age group between 21 and 40 years tho all agc groups were affected.Males and females were equally affected in this study. Malignant tumours were common in adults  over 50 years.The most common benign tumour of keratinocytes  was  seborrhoeic keratosis ,

BCC was most common malignant tumour . Benign appendegeal  tumours  43 (95.55%)  outnumbered malignant counterpart  02(4.44%).   Pilomattricoma was commonest benign appendegeal tumour and clinically seen in younger age group.

Conclusion: Non melanocytic  cutaneous and appendegela tumours commonly  presented in age group    

of  21–40 years  with  no sex predilection. Most lesion presented as nodule in region of head and neck.

Malignant lesion clinically presented as ulcers.Keratinocytic tumours more common than appendegeal tumours Almost all  appendegeal tumours were beign except rare sebaceous carcinomas .Seborrhoic keratosis was commonest keratinocytic  tumour  while pilomatricoma was coomonest  appendegeal  tumour. Histopathological examination  along with clinical  clues is gold standard for diagnosis .