Introduction: Herbal medicine is increasingly common form of alternative therapy throughout the world due to emergence of multidrug resistant bacteria. Licorice( Glycyrrhiza Glabra) commonly known as Yashtimadhu, is one such herb which has medicinal value and was used as a remedy for various ailments from antiquity. Licorice has shown remarkable activity against a large number of organisms, such as bacteria, fungi, viruses, parasites etc. In dentistry, phytomedicines has been commonly used as an anti inflammatory, antibiotic, analgesic and as a sedative agent.

 Objectives: This paper aims at providing comprehensive review on the effects of licorice on common oro dental diseases by reviewing the available data as evidenced in these topics.

Methods: Published literature in English were identified through pubmed, google scholar and World Health Organization website using MeSH terms licorice, dentistry, oral diseases. Out of 210 abstracts only 23 articles were included in this review after applying inclusion and exclusion criteria.

Results and Conclusion:  Due to anti inflammatory, cariostatic, antibacterial, antiplaque, antiviral, antimycotic, ulcer healing, antitumor properties, licorice can prove to be beneficial to treat various oral diseases