Background: The purpose of this study was to analyze the frequency of oral carcinomas over a period of 5 years and to correlate the distribution of OSCC with respect to the site, gender and their association with histological differentiation.

Materials and Methods: Data was obtained from the reports of patients diagnosed with Oral carcinomas between 2014 and 2018 and the following variables were analyzed: frequency of oral carcinomas, gender and site predilection of OSCC and their association with histologic differentiation.

Statistical Analysis: The data was analysed with Statistical Package for Social Sciences (SPSS) for Windows 20.0 (SPSS, Inc. Chicago, Illinois). The observed data was analyzed by Pearson’s Chi square test. Confidence intervals were set at 95% and values of p < 0.05 were interpreted as statistically significant.

Results: In a total of 369 cases of Oral carcinomas, OSCCs were the most common accounting for 351 cases. OSCC was most common among males with the most common site being buccal mucosa followed by lateral border of tongue. Majority of OSCC cases were highly differentiated variants followed by moderate and poorly differentiated variants. The association of gender and site with histological differentiation was found to be insignificant.

Conclusion: This study provides epidemiological information on Oral carcinomas in general and OSCCs in specific at an institutional level. The relative frequency of these OSCCs can be analyzed at a global level to understand their prevalence, incidence, biological behavior and distribution