Retinal disorders are the largest cause of legal blindness in the age group of 20 to 65 years. Approximately 18 million people in India have severely impaired vision due to retinal diseases. It has been nearly 40 years since the principle and techniques of fluorescein angiography were first described. The procedure has now  become standardized and has found a regular place in routine diagnosis of fundus disorders. Objectives : This study was undertaken to assess the evaluate the role of fluorescein angiography and underline it`s advantages over other  conventional methods of ophthalmoscopy in the evaluation of posterior segment diseases. Methods:  A prospective study was done which included 40 patients who attended the OPD during study period. Detailed history was taken from the patient and a thorough ocular and systemic examination was done. Results: 40 cases were analyzed and sub–divided into 3 categories of macular disorders, retinal vascular disorders and inflammatory conditions. FA altered the diagnosis in 13.34%, 50% and 12.5% cases while categorized the lesions in 53.34%, 12.5%  and 62.5% cases  respectively. On statistical analysis, FA proved to be a far superior diagnostic  modality. Conclusions: In the present study we conclude that FA can help to detect cases beyond the reach of clinical ophthalmoscopy.