Chronic  osteomyelitis  remains  a  daunting  challenge  to  orthopaedic surgeons.  It  is  often  described  as  a  disease  that  can  never  truly  be  cured,  particularly  when  the  biological  characteristics  of  the causative  organism  are  taken  into  account. a  single  center  retrospective  cohort  study  was  performed  among  75  patients  diagnosed  with  chronic  osteomyelitis  admitted and   Bone  and  soft  tissues  were  collected  for  cultures.  Patient,   injury,  surgery  associated  variables,  and  microbiological  records were  reviewed  for  risk  factors  associated  with  chronic  osteomyelitis.  The  focus  of  data  collection  was  to  compare characteristics  of  patients  according  to  outcome.