BACKGROUND: Dengue is an exceedingly Anthropod   borne  endemo–epidemic Arboviral infectious disease  in a tropical & sub tropical regions .The objective of study to analyze & correlate clinical as well as haemato–biochemical parameters  in a serologically proven dengue fever patients and to classify severity of disease.

METHODOLOGY: This is an observational, descriptive and retrospective study of 100 patients with clinical and serological  diagnosis with dengue fever  who were NS1 antigen/IgM dengue positive included in a study were admitted in Seth. L.G. hospital during 2018. The presenting clinical symptoms were fever,headache,abdominal pain,diarrhoea,skin rash,itching,seizures and the major physical findings noted were hepatomegaly,bradycardia,pleural effusion, ascites and positive tourniquet test.The tests  conducted and analyzed were complete blood count, S. Protein, LFT,  S.Liver enzymes, RFT, S.electrolytes and urinary R&M.

RESULTS: Thrombocytopenia, raised haemoconcentration, elevated  liver enzymes ,hypoalbumienia  , hyponatremia and  increased urinary albumin excretion  were observed in a patients of dengue fever and dengue haemmorhagic fever/dengue shock syndrome  .

 CONCLUSION:  These tests result were relevant  in assessing severity of the disease and help us to enable specific treatment  form of disease. Fluid management and supportive treatment plays a major role in dengue fever patients whereas platelet transfusion and albumin correction requires in a DHF/DSS patients.