IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-11-17225 Original Research Paper Ischemia modified albumin(IMA)-a sensitive marker in the early diagnosis of Acute coronary syndrom(ACS)? Uday B. Nayak Dr. Dr. Sowmya Mathew Dr. November 2018 7 11 01 02 ABSTRACT

 

Background:

Diagnosing a case of Acute Coronary Syndrome in the emergency department is quite challenging. Early diagnosis and treatment helps in reducing mortality.

Materials and methods:

A total number of 120 patients were included who came to the emergency department with symptoms suggestive of ACS. IMA was done along with the routine work up and compared with the routine cardiac markers.

Results

Mean IMA value was  88.83 + 7.575u/ml in UA group, 87.32 + 9.250u/ml in MI group and 55.96 + 25.332u/ml in NICP group which showed a sensitivity of  92% and specificity of 87% compared to CKMB which was 68% sensitive and 70% specific.  The positive predictive value of the test was 88% and negative predictive value was 94%. In 14 patients an early diagnosis could be made when compared with Trop–I.

Conclusion:

IMA is a very potent marker for the early diagnosis of ACS thus reducing in hospital mortality rates due to delayed diagnosis.