The G6PD enzyme is part of pentose monophosphate shunt. It catalyzes the oxidation of glucose 6 phosphates to nicotinamide adenine dinucleotide phosphate (NADPH) that maintains the glutathione in its reduced form.

Most cases of (G6PD) reported developing acute hemolytic anemia after ingestion of fava bean related foods, certain medication or even during stressful situations.

Here, we report a case of acute hemolytic anemia occurred after ingestion of FALAFEL sandwich (a fava bean product), that was associated with methemoglobinemia.  This rare coexistence of both diseases with only 5 cases reported in pediatric age group. Mother was informed about the diagnosis of G6PD in primary health care center when the patient was two years old but wasn’t sure about it. After reviewing the literature for similar cases, we concluded that there were no other reported cases with the same presentation and good outcome