IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-12-17346 Original Research Paper Clinicopathological Profile of soft tissue sarcoma in a Pediatric age group among those who attended health institutions in North india Showkat Majeed Dr. Dr. Sajad Dr. December 2018 7 12 01 02 ABSTRACT

 

Background: Soft tissue sarcomas are a rare group of heterogeneous tumours that consist of several neoplasia which differentiate into different cell lines. They could arise from the mesodermal or ectodermal embryonic germ layers. Rhabdomyosarcoma is the most common soft tissue tumour in the paediatric age group in most studies, while in adults, malignant fibrous histocytoma, liposarcoma and fibrosarcoma are seen to be more predominant. The study aims to highlight the histological patterns, clinical presentation, associated risk factors and the patients’ performance status at presentation.

Methods: This is a  retrospective Study  of all cancer patients diagnosed with soft tissue sarcoma at a tertiary health centre  Data collected included socio–demographic, histological type, clinical features, and performance status.

Results: A total of 64 patients were reviewed during the study period  and 4 patients were diagnosed suffering from soft tissue sarcoma.(6.25%).50% cases seen in 2–4 year age group with equal gender preponderance(male:female;50:50).Rural and urban also show 50:50 incidence. Abdominal mass  weight loss were main symptoms.Pallor was the main sign (75%).Investigations like USG reveal distortion of architecture & Cct Showed either the disease is localized /extent demarcated.50% CASES WERE IN Stage I Disease as per International soft tissue sarcoma study group.75% cases were operable showing the tumour was located retroperitoneally or arised from bladder wall.Complete excision was done in those cases with localized retroperitoneal disease followed by histopathology.

Conclusions: Rhabdomyosarcoma was the most predominant histological type of soft tissue sarcoma seen over the review