Introduction: acute appendicitis is a common surgical emergency. Measurement of blood CRP level can aid in getting the right diagnosis.

Material and methods: 80 patients of acute appendicitis who underwent appendectomy were included in this study. Preoperative CRP was measured in each case and postoperative HPE examination of excised specimen was done.

Results: acute appendicitis is more common in young females. Clinical diagnosis of acute appendicitis has accuracy of 85%. CRP level measurement can increase the diagnosis of acute appendicitis up to accuracy of 93.7%.

Discussion and conclusion: Blood CRP level measurement has been studied in many researches as an aid to clinical methods in diagnosis of acute appendicitis. This study concludes that CRP can help in the diagnosis especially in cases of severe form of acute appendicitis.