Introduction:

 Plasmapheresis is usually well tolerated. Occasionally, Adverse Events (AEs) of variable severity may occur during or after the procedure. AEs that occur in Donors are divided into local reactions and systemic reactions.

Materials and Methods:

A total of 57 apheresis procedures were performed in a period of one year study. All the adverse reactions occurring during this period were documented.

Results:

All the donors in our study were male. Out of 57, 5 suffered adverse reaction. The incidence of adverse effects was 8.77% in our study. None of these reactions was life threatening and none of the procedure was needed to be halted in between because of them.

Conclusion:

Plateletpheresis  procedures performed on cell separator are safe, with a low incidence of significant AEs.