Background:Percutaneous injury with an infected sharp device can lead to exposure of the health care worker (HCW) to various blood borne pathogens

Aims and Objectives: To review the pattern of needle stick injuries (NSIs) and to study the impact of interventions on the needle stick injuries

Material & Method: All NSIs were documented and monitored as per the occupational exposure to blood borne pathogen reporting policy of the hospital.Impact of various interventions was noted

Result:During a 5 year period, 276 health care workers reported NSIs.Due to increased awareness the reporting of NSIs increased. There was a decrease in the NSIs occured while handling Bio Medical Waste (BMW) after the introduction of on–site small puncture proof sharp containers and after the introduction of retractable BSL device.Reporting of NSI within 2 hours of exposure was improved to 95% resulting in timely provision of post exposure prophylaxis.Hepatitis B immunization status of exposed HCWs improved after hospital wide Hepatitis B immunization programme