Background:– Inhalational  organophosphorus  (OP)  compound  poisoning  was  suddenly raised  up to  epidemic  proportion  in  Yavatmal  district  in  2017.  During  this  crop  year  2018, the  incidence  of  inhalational  OP  poisoning  was  drastically  decreased  below  30%. Randomized,  retrospective,  observational  study  was  carried  out  to  find  the  cause  of  this drastic  change.

Methods:– Thorough  study  of  the  case  papers  of  inhalational  OP  poisoning  patients  from the  record  section  and  HMIS  of  S.V.N.G.M.C.  Yavatmal  was  done.  Complete  data  was collected  and  interpreted.  Analysis  of  data  done  on  seven  points,  sprayer’s  bio data, insecticide  used,  spray  pump  used,  seed/crop  conditions,  environmental  conditions, treatment  part  and  preventive  measures  by  the  Agricultural  department.

Results:–Data  collected  from  July  2018  to  November  2018.  Maximum  number  of  cases were  admitted  in  September  2018.  Total  166  cases  were  admitted  and  no  death reported.  Majority  of  them  were  professional  sprayers  and  at  this  time  they  had  taken intra  and  post  procedural  precautions.  Endosulfan  was  the  commonly  used  insecticide. Large  amount  of  Pralidoxime  and  small  amount  of  Atropine  was  used  for  treatment. Environmental  factors  and  preventive  measures  by  Agricultural  department  played  vital role  in  this  drastic  change.

Conclusion:–Spraying  precautions  given  by  the  Agricultural  department,  environmental factors,  control  of  adulteration  and  good  work  by  medical  staff  decreased  the  case  load in  2018.