Background: Cranioplasty is done after therapeutic decompressive cranieotomy (DC) to protect  brain and  for cosmetic purpose. The autologous bone is kept in the subcutaneous plane in anterior abdominal wall.

Methods: It was a Prospective study with a total 50 patients were included  after inclusion and exclusion criteria were met between 2016 to 2018. Gross and microscopic changes in the bone were noted.

Results: Men constituted 78% of the study group. There is statistically significant reduction in length (p=0.025), width (p=0.021), thickness (p=0.012) and weight (p=0.04) measured in patients who underwent cranioplasty 3 months after initial surgery compared to patients who underwent cranioplasty on or < 3 months of initial surgery. Only 6% of patients showed necrotic changes.

Conclusion: There is significant reduction in length, width, thickness and weight of bone measured in patients who underwent cranioplasty 3 months after initial surgery compared to less then 3 months of initial DC.