IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-7-12-17504 Original Research Paper A Study of Improvement of Cervical Mucus with Guaifenesin In Infertility Patients Dr. December 2018 7 12 01 02 ABSTRACT

 

Aim:

  1. To assess the effect of Guaifenesin in improving the cervical mucus in patients with infertility due to cervical factor.
  2. It thins out cervical mucus and reduces viscosity. It should be taken 5 days prior to ovulation and continued until ovulation has occurred.
  3. A total of 40 couples with minimum period of 1 year infertility were included in this study. The study was conducted in MIMS, Vikarabad.

 

Material & Methods:

Ø  A total of 40 couples were included in this study.

Ø  Infertility with anovulation with or without poor cervical score were included in the study.

Results :

Pregnancy Rates after Two or Three Cycles        

Ø   Group I                :               4/12       33%

Ø  Group II               :               8/24       33%

Ø   24 out of 36 patients showed marked improvement in PCT and six patients had slight improvement in mucus quality and PCT.

Ø   No improvement seen in Six Patients.

Conclusions:

  1. Guaifenisin improves cervical mucus and there by fertility rates.
  2. It is a very safe drug with less side effects only three patients reported nausea and GI upset in our study.
  3. Cost effective when compared to other infertility drugs.
  4. Easy to infer the results and can be done as OP procedure.