Nocardiosis is an infectious disease that occurs in cutaneous, pulmonary and disseminated forms. It is usually associated with host defense defect. Infection arises by direct skin inoculation or inhalation. Immunocompromised status, alcoholism & certain lung diseases predispose to pulmonary & CNS nocardiosis. Our patient was a 70 yr old alcoholic male suffering from dermatomyositis for which he was on prolonged oral steroids. He had lung infection with CNS spread, which was diagnosed as Nocardiosis. He was put on high dose Trimethoprim– Sulphamethoxazole, Meropenem and Ceftriaxone. With appropriate treatment, the mortality rate for pulmonary or disseminated nocardiosis outside the CNS can be significantly decreased. Cure  rates  of almost  100%  are  found  in  patients  with  skin  or  soft  tissue  involvement, compared  with  90%  in  pulmonary  disease,  63%  in  disseminated infection,  and  50%  in  brain  abscess. CNS disease carries a higher mortality rate.