A new technique of caries removal has been introduced in dentistry recently due to the advances and development of more preservative method of caries removal. Instead of using old methods of drilling and cutting, this new technique involves chemico–mechanical removal of infected tooth structure using material like Carisolv. Application of carisolv will make the patient more comfortable while caries removal as less pain occurs while excavating the caries using carisolv. Further, Carisolv allows removal of only infected dentin and preservation of affected dentin which can be reminiralized in the future. Thus, Carisolv is considered as a minimal invasive approach of treating the dental caries. This review includes the study conducted in the recent years comparing the conventional or mechanical method versus chemico–mechanical method using Carisolv.