IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-1-17611 Original Research Paper CLINICAL SIGNIFICANCE OF SERUM VITAMIN D LEVEL IN PATIENTS OF VITILIGO AT TERTIARY CARE CENTRE, SURAT, INDIA Sanjay Dr. January 2019 8 1 01 02 ABSTRACT

 

Background: Vitiligo is an acquired, idiopathic, heritable depigmentary disorder of the skin and/or mucous membranes. Autoimmunity plays an important role in pathogenesis of vitiligo which is also evident by coexistence of various autoimmune disorders with vitiligo. In turn, vitamin D levels have been found to be reduced in various autoimmune disorders, thus pointing to a plausible association between vitiligo and vitamin D levels. Few reports have evaluated serum vitamin D levels in vitiligo and their results are conflicting.

Aim: To study clinico‑epidemiological profile and to evaluate serum vitamin D levels of vitiligo patients and compare vitamin D level with control.

Methods: Total 25 patients clinically diagnosed with vitiligo were enrolled in study and 25 age and sex matched control were included. Results were carried out using STATA version 14.2

Results: The patients had lower serum vitamin D levels than the controls, but this difference was not statistically significant. (p = 0.557)

Conclusions: Significantly lower vitamin D levels were found in majority of vitiligo patients, but this was not significant.