Prostatic calcification is most commonly encountered as calculus or intraluminal calcifications within atypical small glandular proliferations. This study was undertaken to detect stromal microcalcifications in prostate tissue. All slides from 56 biopsies were retrospectively reviewed. Association with prostatic glands was not seen in any of the microcalcification foci. Two cases had simultaneous adenocarcinoma and one had high–grade prostatic intraepithelial neoplasia, all of which were apart from the microcalcification foci. In conclusion, stromal microcalcification is a dystrophic, inflammation–mediated, benign process.