Background:                                                                                                                             Intra–abdominal masses always remain as an enigma in surgical practice. A documentary evidence of the nature of the pathology before the institution of therapy and for the prognosis is mandatory. FNAC is a substitute for surgical procedures like diagnostic laparotomy or laproscopic biopsy. Fine needle aspiration cytology (FNAC) with assistance of radiological tools such as ultrasonography (USG) and computed tomography (CT) is an effective and safe technique for diagnosing intra–abdominal neoplastic and nonneoplastic lesions.

Aims and Objectives:                                                                                                                              (1) To assess the utility of image–guided cytology in the diagnosis of intra–abdominal lesions.                                                                                                          (2) To categorize various intra–abdominal lesions according to their site of occurrence and study their cytomorphological features.

Materials and Methods:                                                                                                       A Retrospective  study was conducted in the Department of Pathology between January 2018 to  December 2018. A total of 42 cases with intra–abdominal lesions were included in the study.

Results:                                                                                                                                   In our study, diagnostic yield was 85.8%. The mean age was found to be 51.1 years with M: F ratio 2.4:1. We found that 25 (59.5%) cases were in hepato–biliary region, 14 (33.3%) in lymph nodes,  3 (7.1%) in unknown abdominal lumps. Of total 42 cases, 23 (54.7%) cases were malignant, 5 (11.9%) benign, 8 (19.0%) inflammatory, 6 (14.2%) inadequate.

Conclusion:                                                                                                                         Guided FNAC was thus confirmed as a safe procedure that provides fairly accurate diagnosis with minimal complications in the diagnosis of intra–abdominal and retroperitoneal lesions.