IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-1-17856 Original Research Paper Peptic Ulcer Disease in Cirrhosis D Dr. Karki S Dr. January 2019 8 1 01 02 ABSTRACT

 

Introduction

Peptic ulcer bleed (PUB) is associated with increased mortality in both compensated and decompensated cirrhosis. Knowing the frequency of Peptic Ulcer Disease (PUD) and accurate documentation of bleeding source will avoid inappropriate therapeutic procedure in patients with cirrhosis and gastrointestinal bleeding while missing the diagnosis results in fatal outcome. This study is conducted to describe the prevalence of PUD in cirrhosis .

 

Method

This is a retrospective study that included 199 patients with chronic liver disease (CLD) referred to upper gastrointestinal (UGI) endoscopy during last 6 months. The primary end point was to describe prevalence of PUD among these patients. The secondary end point was to evaluate the association between PUD, child’s class and portal hypertensive gastropathy (PHG)

 

Result

The prevalence of PUD in patients with cirrhosis was 32.1 % and its prevalence according to Child Pugh A, B and C was 18.8, 42.2 and 39.1 % respectively. The occurrence of PUD with respect to presence and absence of PHG is 34.2 and 26 % respectively.

 

Conclusion

There is high prevalence of PUD in CLD. However, there is no statistically significant correlation between PUD, Child’s class and PHG.