IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-2-17933 Original Research Paper Study of Total Antioxidants Capacity of serum in hyperuricemia patients without Gout Agarwal Dr. Vinod Kumar Dr. February 2019 8 2 01 02 ABSTRACT

 

The antioxidants like Vitamin C, tocopherol, bilirubin uric acid glutathione peroxidase prevent free radical damage to proteins, carbohydrates, lipids and DNA by scavenging them. Uric acid is an antioxidant but may cause gout. The study includes 40 hyperuricemia patients without gout to exclude inflammation associated with gout and equal number of controls. The concentration of trolox antioxidant capacity was measured by chemical method. Uric acid level was measured with auto analyzer. It has been found that there is significant increase in trolox antioxidant capacity among hyperuricemia patients which is statistically highly significant (p<0.0001). Researchers have observed that hyperuricemia even without gout may damage to various organs such as heart. The study concludes that even though there is increase in trolox antioxidant capacity(TAC) but in spite this increase there is no benefit to the heath as proved by earlier studies.