Background  

Sexual dysfunction in schizophrenia may be a consequence of many factors; the condition itself, its socioeconomic impact & its treatment. Antipsychotics can induce side effect by blocking dopamine receptor may lead to amenorrhoea, galactorrhoea, sexual dysfunction, and osteoporosis.

Aim: To assess sexual dysfunction and Prolactin among antipsychotic medicines treated male schizophrenic patients.

Methods: A total 82 schizophrenic male were assessed for sexual dysfunction Psychotropic–Related Sexual Dysfunction Questionnaire (PRSexDQ–Salsex) and prolactin by ELISA method.

Results:

Here approximately 75.6% had sexual dysfunction, 42.7% (35) having moderate, 28% (23) mild and 4.9% (4) severe sexual dysfunction. The prolactin level was significantly higher in patients treated with Risperidone (75%) than compared to the combination of antipsychotics (55%) and only with olanzapine (17.6%).

Conclusions: Antipsychotic medicines have a great impact on sexual function. All healthcare professionals encourage to address sexual symptoms prior to the prescription of antipsychotics and on follow–up to improve treatment adherence.