Urolithiasis is a worldwide problem, due to its high prevalence and frequency of recurrence. Day to day advances in technology have made treatment of urolithiaisis less and less invasive with decreasing morbidity.

AIM: To compare Percutaneous Nephrolithotomy and minimally invasive–Percutaneous Nephrolithotomy as treatment modalities of Nephrolithiasis

MATERIAL AND METHODS : This study was  done among patients of renal calculi admitted in the Department of Surgery at S.N. Medical College, Agra during the period from January 2017 to December 2017 follow up for 3 months Total of 150 cases were enrolled in the study and divided into 2 groups, Group A having 75 patients who underwent mini PCNL and Group B having 75 patients treated with PCNL.

DISCUSSION–Mean drop in hemoglobin level and bleeding necessitated blood transfusion were significantly lower in the mini PCNL group. Duration of hospital stay were lesser for mini–PCNL .

CONCLUSION– Mini PCNL is effective for managing renal calculi with comparable operative time and stone free rate to standard PCNL with the merit of higher safety due to lower incidence of bleeding and early discharge.