Many studies have predicted a host of factors that precipitate the development of cardiovascular (CVD) and Diabetes Mellitus (DM). Some studies have also recommended preventive measures to avoid such diseases. The risk factors that accelerate Type 2 Diabetes Mellitus (T2DM) are high Blood Pressure (BP); Sedentary lifestyle, obesity, elevated cholesterol, family history and ageing. Both CVD and DM could be easily prevented if certain established protocols are followed. This review article gives a condensed summary of research work done during the last two decades on the preventive measures and their effects in reducing the morbidity and mortality associated with CVD and DM. More researches are required in this field to establish consensus guidelines that could be effectively followed in all cardio and diabetes clinics