Background: In recent years, periodontal disease has been implicated in the onset and development of cardiovascular disease. Aim of this study was to assess the periodontal status, in acute myocardial infarction (AMI) patients and its association with the levels of hs–CRP and fibrinogen.

Methods: 200 patients, diagnosed with AMI by cardiologist were included in the study. Periodontal status was recorded using Ramjford’s Periodontal Disease Index. hs–CRP levels were assessed using immunoturbidometric assay and fibrinogen levels by coagulation assay.

Results: Elevated levels of hs–CRP were found in 22.5% of patients with gingivitis and 96.8% of patients with periodontitis, which was statistically significant. Elevated levels of fibrinogen were found in 12.5% of patients with healthy gingiva 15% of patients with gingivitis and 75% of periodontitis patients which was statistically significant. 

Conclusion: Elevated levels of hs–CRP and fibrinogen in AMI patients with periodontitis suggested significant association of periodontitis with hs–CRP and fibrinogen levels.